InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LGALS3BP

Summary

InnateDB Protein

IDBP-695284.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LGALS3BP

Protein Name

Galectin-3-binding protein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001802

InnateDB Gene

IDBG-642788 (LGALS3BP)

Protein Structure

UniProt Annotation

Function

Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005044	scavenger receptor activity
GO:0005515	protein binding

Biological Process

GO:0006898	receptor-mediated endocytosis
GO:0007155	cell adhesion

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0016020	membrane
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR001190 SRCR domain
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
IPR017448 SRCR-like domain

PFAM

PF00530
PF07707

PRINTS

PR00258

PIRSF

SMART

SM00225
SM00875
SM00202

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A7E3W2

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

531137

UniGene

Bt.6597

RefSeq

NP_001039781

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC105367 BT030733

GenPept

AAI05368 ABS45049