InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TK1

Summary

InnateDB Protein

IDBP-695427.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TK1

Protein Name

Thymidine kinase, cytosolic

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000034599

InnateDB Gene

IDBG-642922 (TK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 142 interaction(s) predicted by orthology.

Predicted by orthology
Total	142 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004797	thymidine kinase activity
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0019206	nucleoside kinase activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006260	DNA replication
GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
GO:0009165	nucleotide biosynthetic process
GO:0016310	phosphorylation
GO:0051289	protein homotetramerization

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001267 Thymidine kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00265

PRINTS

PIRSF

PIRSF035805

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A5D7R8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

504652

UniGene

Bt.964

RefSeq

NP_001091041

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC140658 BT030694

GenPept

AAI40659 ABS45010