Version 5.4
Bos taurus Protein: DCK
Summary
InnateDB Protein IDBP-695465.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCK
Protein Name Deoxycytidine kinase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000016449
InnateDB Gene IDBG-642952 (DCK)
Protein Structure
UniProt Annotation
Function Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004137 deoxycytidine kinase activity
GO:0005524 ATP binding
GO:0008144 drug binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0019206 nucleoside kinase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006220 pyrimidine nucleotide metabolic process
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002624 Deoxynucleoside kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF01712
PRINTS
PIRSF PIRSF000705
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHR2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 530642
UniGene Bt.27090
RefSeq NP_001029745
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105141
GenPept AAI05142

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca