InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC4A4

Summary

InnateDB Protein

IDBP-695473.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC4A4

Protein Name

electrogenic sodium bicarbonate cotransporter 1

Synonyms

NBC1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003032

InnateDB Gene

IDBG-642956 (SLC4A4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005452	inorganic anion exchanger activity
GO:0005515	protein binding
GO:0008509	anion transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006814	sodium ion transport
GO:0006820	anion transport
GO:0015701	bicarbonate transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003020 Bicarbonate transporter, eukaryotic
IPR003024 Sodium bicarbonate cotransporter
IPR011531 Bicarbonate transporter, C-terminal
IPR013769 Band 3 cytoplasmic domain
IPR016152 Phosphotransferase/anion transporter

PFAM

PF00955
PF07565

PRINTS

PR01231
PR01232

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite