Version 5.4
Bos taurus Protein: SEPT11
Summary
InnateDB Protein IDBP-695664.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT11
Protein Name Septin-11
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005626
InnateDB Gene IDBG-643132 (SEPT11)
Protein Structure
UniProt Annotation
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). {ECO:0000250, ECO:0000305}.
Subcellular Localization Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051291 protein heterooligomerization
GO:0051301 cell division
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030054 cell junction
GO:0030424 axon
GO:0031105 septin complex
GO:0042995 cell projection
GO:0043197 dendritic spine
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000038 Cell division protein GTP binding
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00735
PRINTS
PIRSF PIRSF006698
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2VE99
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 535746
UniGene Bt.102100
RefSeq NP_001075916
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133640
GenPept AAI33641

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca