Version 5.4
Bos taurus Protein: HPSE
Summary
InnateDB Protein IDBP-695774.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HPSE
Protein Name heparanase precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007550
InnateDB Gene IDBG-643229 (HPSE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0030305 heparanase activity
GO:0045545 syndecan binding
GO:0046983 protein dimerization activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007160 cell-matrix adhesion
GO:0010575 positive regulation vascular endothelial growth factor production
GO:0030194 positive regulation of blood coagulation
GO:0030200 heparan sulfate proteoglycan catabolic process
GO:0033690 positive regulation of osteoblast proliferation
GO:0042060 wound healing
GO:0051797 regulation of hair follicle development
GO:0051798 positive regulation of hair follicle development
GO:0051897 positive regulation of protein kinase B signaling
GO:0060055 angiogenesis involved in wound healing
GO:0061042 vascular wound healing
Cellular Component
GO:0005634 nucleus
GO:0005764 lysosome
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID
InterPro IPR005199 Glycoside hydrolase, family 79
IPR017853 Glycoside hydrolase, superfamily
PFAM PF03662
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N1G1
UniProt Splice Variant
Entrez Gene 281230
UniGene Bt.8127
RefSeq NP_776507
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02018273 DAAA02018274
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca