Version 5.4
Bos taurus Protein: RAB3IL1
Summary
InnateDB Protein IDBP-696103.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB3IL1
Protein Name Guanine nucleotide exchange factor for Rab-3A
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020909
InnateDB Gene IDBG-643541 (RAB3IL1)
Protein Structure
UniProt Annotation
Function Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0032851 positive regulation of Rab GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR009449 GDPGTP exchange factor Sec2p
IPR010978 tRNA-binding arm
PFAM PF06428
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KJ58
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614335
UniGene Bt.9335
RefSeq NP_001039997
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105507
GenPept AAI05508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca