InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FN1

Summary

InnateDB Protein

IDBP-696249.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FN1

Protein Name

fibronectin

Synonyms

FN;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010925

InnateDB Gene

IDBG-643655 (FN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 605 interaction(s) predicted by orthology.

Predicted by orthology
Total	605 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0016504	peptidase activator activity

Biological Process

GO:0007044	cell-substrate junction assembly
GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007161	calcium-independent cell-matrix adhesion
GO:0010952	positive regulation of peptidase activity
GO:0018149	peptide cross-linking
GO:0034446	substrate adhesion-dependent cell spreading
GO:0042060	wound healing
GO:0045773	positive regulation of axon extension

Cellular Component

GO:0005576	extracellular region
GO:0005577	fibrinogen complex
GO:0005604	basement membrane
GO:0005605	basal lamina
GO:0005615	extracellular space
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0016324	apical plasma membrane
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR000083 Fibronectin, type I
IPR000562 Fibronectin, type II, collagen-binding
IPR003961 Fibronectin, type III
IPR013806 Kringle-like fold

PFAM

PF00039
PF00040
PF00041
PF01108

PRINTS

PIRSF

SMART

SM00058
SM00059
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9MZ31

UniProt Splice Variant

Entrez Gene

280794

UniGene

Bt.23418

RefSeq

XP_005202834

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB099071 AF136453 AF260305 AY221633 DAAA02005870 DQ347566

GenPept

AAD33692 AAF91381 AAO72631 ABC55275 BAC56561