Version 5.4
Bos taurus Protein: DSG2
Summary
InnateDB Protein IDBP-696321.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSG2
Protein Name desmoglein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029228
InnateDB Gene IDBG-643742 (DSG2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086069 bundle of His cell to Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030057 desmosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR009122 Desmosomal cadherin
IPR009123 Desmoglein
IPR015919 Cadherin-like
PFAM PF01049
PF00028
PRINTS PR00205
PR01818
PR01819
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MFC2
UniProt Splice Variant
Entrez Gene 508151
UniGene Bt.90097
RefSeq NP_001179101
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02056456 DAAA02056457
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca