Version 5.4
Bos taurus Protein: ATP5I
Summary
InnateDB Protein IDBP-696359.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP5I
Protein Name ATP synthase subunit e, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000023255
InnateDB Gene IDBG-643777 (ATP5I)
Protein Structure
UniProt Annotation
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Subcellular Localization Mitochondrion. Mitochondrion inner membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015078 hydrogen ion transmembrane transporter activity
Biological Process
GO:0006754 ATP biosynthetic process
GO:0006810 transport
GO:0006811 ion transport
GO:0015986 ATP synthesis coupled proton transport
GO:0015992 proton transport
Cellular Component
GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005753 mitochondrial proton-transporting ATP synthase complex
GO:0016020 membrane
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
Protein Structure and Domains
PDB ID
InterPro IPR008386 ATPase, F0 complex, subunit E, mitochondrial
PFAM PF05680
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q00361
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 338040
UniGene
RefSeq NP_788812
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102279 M64751
GenPept AAA30390 AAI02280

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca