Version 5.4
Bos taurus Protein: CTBP1
Summary
InnateDB Protein IDBP-696477.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTBP1
Protein Name C-terminal binding protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000011166
InnateDB Gene IDBG-643874 (CTBP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.
Predicted by orthology
Total 84 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019904 protein domain specific binding
GO:0048037 cofactor binding
GO:0051287 NAD binding
GO:0070491 repressing transcription factor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006098 pentose-phosphate shunt
GO:0008152 metabolic process
GO:0031065 positive regulation of histone deacetylation
GO:0034401 regulation of transcription by chromatin organization
GO:0035067 negative regulation of histone acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050872 white fat cell differentiation
GO:0051726 regulation of cell cycle
GO:0055114 oxidation-reduction process
GO:0090241 negative regulation of histone H4 acetylation
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
PFAM PF03446
PF00389
PF02826
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MYP4
UniProt Splice Variant
Entrez Gene 513131
UniGene
RefSeq XP_002688496
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT030570 DAAA02018538 DAAA02018539
GenPept ABQ13010

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca