Version 5.4
Bos taurus Protein: BT.22104
Summary
InnateDB Protein IDBP-696523.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.22104
Protein Name Indian hedgehog homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000011124
InnateDB Gene IDBG-643926 (BT.22104)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005113 patched binding
GO:0005509 calcium ion binding
GO:0008233 peptidase activity
Biological Process
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0001569 patterning of blood vessels
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001708 cell fate specification
GO:0001763 morphogenesis of a branching structure
GO:0001944 vasculature development
GO:0001947 heart looping
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003382 epithelial cell morphogenesis
GO:0003406 retinal pigment epithelium development
GO:0006029 proteoglycan metabolic process
GO:0006508 proteolysis
GO:0007154 cell communication
GO:0007224 smoothened signaling pathway
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
GO:0007389 pattern specification process
GO:0008284 positive regulation of cell proliferation
GO:0009880 embryonic pattern specification
GO:0016539 intein-mediated protein splicing
GO:0030154 cell differentiation
GO:0030704 vitelline membrane formation
GO:0031016 pancreas development
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033085 negative regulation of T cell differentiation in thymus
GO:0033088 negative regulation of immature T cell proliferation in thymus
GO:0033089 positive regulation of T cell differentiation in thymus
GO:0035264 multicellular organism growth
GO:0035988 chondrocyte proliferation
GO:0040008 regulation of growth
GO:0043010 camera-type eye development
GO:0045453 bone resorption
GO:0045596 negative regulation of cell differentiation
GO:0045880 positive regulation of smoothened signaling pathway
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046638 positive regulation of alpha-beta T cell differentiation
GO:0046639 negative regulation of alpha-beta T cell differentiation
GO:0048074 negative regulation of eye pigmentation
GO:0048469 cell maturation
GO:0048557 embryonic digestive tract morphogenesis
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048666 neuron development
GO:0048745 smooth muscle tissue development
GO:0051216 cartilage development
GO:0060220 camera-type eye photoreceptor cell fate commitment
GO:0060323 head morphogenesis
GO:0061053 somite development
GO:0072498 embryonic skeletal joint development
GO:0090136 epithelial cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000320 Hedgehog, N-terminal signalling domain
IPR001657 Hedgehog protein
IPR001767 Hedgehog protein, Hint domain
IPR003586 Hint domain C-terminal
IPR003587 Hint domain N-terminal
IPR006141 Intein splice site
IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain
IPR028992 Hedgehog/Intein (Hint) domain
PFAM PF01085
PF01079
PRINTS PR00632
PIRSF PIRSF009400
SMART SM00305
SM00306
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6QA78
UniProt Splice Variant
Entrez Gene 522714
UniGene Bt.22104
RefSeq NP_001070338
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02005940 DAAA02005941
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca