Version 5.4
Bos taurus Protein: GTF2F1
Summary
InnateDB Protein IDBP-696569.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2F1
Protein Name ral transcription factor IIF subunit 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027988
InnateDB Gene IDBG-643971 (GTF2F1)
Protein Structure
UniProt Annotation
Function TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR008851 Transcription initiation factor IIF, alpha subunit
IPR011039 Transcription Factor IIF, Rap30/Rap74, interaction
PFAM PF05793
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5EA53
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505702
UniGene Bt.3359
RefSeq NP_001015527
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146189 BT020716
GenPept AAI46190 AAX08733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca