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InnateDB Protein
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IDBP-696852.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FBXO32
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Protein Name
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F-box only protein 32
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000021554
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InnateDB Gene
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IDBG-644229 (FBXO32)
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Protein Structure
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| Function |
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between Cytoplasm and the nucleus. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 126 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
126 [view]
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Molecular Function |
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| Biological Process |
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GO:0014894
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response to denervation involved in regulation of muscle adaptation
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GO:0016567
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protein ubiquitination
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GO:0071549
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cellular response to dexamethasone stimulus
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001810
F-box domain
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| PFAM |
PF00646
PF12937
PF13013
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| PRINTS |
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| PIRSF |
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| SMART |
SM00256
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q2KHT6
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
513776
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| UniGene |
Bt.91269
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| RefSeq |
NP_001039620
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
BC112888
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| GenPept |
AAI12889
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Version 5.4