Version 5.4
Bos taurus Protein: IL5
Summary
InnateDB Protein IDBP-697330.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL5
Protein Name Interleukin-5
Synonyms IL-5; TRF;
Species Bos taurus
Ensembl Protein ENSBTAP00000041739
InnateDB Gene IDBG-644678 (IL5)
Protein Structure
UniProt Annotation
Function Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005137 interleukin-5 receptor binding
GO:0005515 protein binding
GO:0008083 growth factor activity
Biological Process
GO:0006955 immune response
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051024 positive regulation of immunoglobulin secretion
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0071803 positive regulation of podosome assembly
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR000186 Interleukin-5
IPR009079 Four-helical cytokine-like, core
PFAM PF02025
PRINTS PR00432
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P52173
PhosphoSite PhosphoSite-
TrEMBL B5LVM9
UniProt Splice Variant
Entrez Gene 280825
UniGene Bt.5
RefSeq NP_776347
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL EU276070 EU914955 EU914956 EU914957 EU914958 EU914959 EU914960 EU914967 EU914968 EU914969 EU914970 EU914971 EU914972 EU914973 EU914974 EU914979 EU914980 EU914981 EU914982 EU914983 EU914984 EU914985 EU914986 EU914991 EU914992 EU914993 EU914994 EU914995 EU914996 EU914997 EU914998 EU914999 EU915000 EU915003 EU915004 EU915005 EU915006 EU915007 EU915008 EU915009 EU915010 EU915015 EU915016 EU915017 EU915018 EU915019 EU915020 EU915021 EU915022 EU915025 EU915026 EU915027 EU915028 EU915029 EU915030 EU915031 EU915032 EU915037 EU915038 EU915039 EU915040 EU915041 EU915042 EU915043 EU915044 Z67872
GenPept ABX72068 ACH53199 ACH53200 ACH53201 ACH53202 ACH53203 ACH53204 ACH53211 ACH53212 ACH53213 ACH53214 ACH53215 ACH53216 ACH53217 ACH53218 ACH53223 ACH53224 ACH53225 ACH53226 ACH53227 ACH53228 ACH53229 ACH53230 ACH53233 ACH53234 ACH53235 ACH53236 ACH53237 ACH53238 ACH53239 ACH53240 ACH53241 ACH53242 ACH53245 ACH53246 ACH53247 ACH53248 ACH53249 ACH53250 ACH53251 ACH53252 ACH53257 ACH53258 ACH53259 ACH53260 ACH53261 ACH53262 ACH53263 ACH53264 ACH53267 ACH53268 ACH53269 ACH53270 ACH53271 ACH53272 ACH53273 ACH53274 ACH53279 ACH53280 ACH53281 ACH53282 ACH53283 ACH53284 ACH53285 ACH53286 CAA91779

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca