Version 5.4
Homo sapiens Protein: IMP4
Summary
InnateDB Protein IDBP-69752.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMP4
Protein Name IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000259239
InnateDB Gene IDBG-69750 (IMP4)
Protein Structure
UniProt Annotation
Function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. {ECO:0000269PubMed:12655004}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:12655004, ECO:0000269PubMed:16533400}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005730 nucleolus
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID
InterPro IPR004154 Anticodon-binding
IPR007109 Brix domain
PFAM PF03129
PF04427
PRINTS
PIRSF
SMART SM00879
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96G21
PhosphoSite PhosphoSite-Q96G21
TrEMBL B9A008
UniProt Splice Variant
Entrez Gene 92856
UniGene Hs.91579
RefSeq NP_219484
HUGO HGNC:30856
OMIM 612981
CCDS CCDS2160
HPRD 10002
IMGT
EMBL AC132479 AK289878 AK292345 AK312808 AY364245 BC010042
GenPept AAH10042 AAQ76804 AAY24076 BAF82567 BAF85034 BAG35666

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca