InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EOGT

Summary

InnateDB Protein

IDBP-697748.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EOGT

Protein Name

Uncharacterized glycosyltransferase AER61

Synonyms

AER61; C22H3orf64;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000030725

InnateDB Gene

IDBG-645063 (EOGT)

Protein Structure

UniProt Annotation

Function

Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016262	protein N-acetylglucosaminyltransferase activity
GO:0016740	transferase activity
GO:0016757	transferase activity, transferring glycosyl groups

Biological Process

GO:0006493	protein O-linked glycosylation
GO:0008152	metabolic process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

InterPro

IPR007657 Glycosyltransferase AER61, uncharacterised

PFAM

PF04577

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A0JND3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

508782

UniGene

Bt.70023

RefSeq

NP_001071350

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC126625

GenPept

AAI26626