InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SFXN1

Summary

InnateDB Protein

IDBP-697752.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SFXN1

Protein Name

Sideroflexin-1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000019322

InnateDB Gene

IDBG-645072 (SFXN1)

Protein Structure

UniProt Annotation

Function

Might be involved in the transport of a component required for iron utilization into or out of the mitochondria. {ECO:0000250}.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008324	cation transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006812	cation transport
GO:0006826	iron ion transport
GO:0030218	erythrocyte differentiation
GO:0055072	iron ion homeostasis
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004686 Tricarboxylate/iron carrier

PFAM

PF03820

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9M8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

511375

UniGene

Bt.633

RefSeq

NP_001015574

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103181 BT020892

GenPept

AAI03182 AAX08909