InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: COL4A3BP

Summary

InnateDB Protein

IDBP-697765.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COL4A3BP

Protein Name

Collagen type IV alpha-3-binding protein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000092

InnateDB Gene

IDBG-645085 (COL4A3BP)

Protein Structure

UniProt Annotation

Function

May mediate the intracellular trafficking of ceramide in a non-vesicular manner. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Note=Preferentially localized to the Golgi apparatus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0016301	kinase activity
GO:0035620	ceramide transporter activity
GO:0070273	phosphatidylinositol-4-phosphate binding
GO:0097001	ceramide binding

Biological Process

GO:0000902	cell morphogenesis
GO:0001701	in utero embryonic development
GO:0003007	heart morphogenesis
GO:0006672	ceramide metabolic process
GO:0006810	transport
GO:0006869	lipid transport
GO:0006936	muscle contraction
GO:0007029	endoplasmic reticulum organization
GO:0007165	signal transduction
GO:0008283	cell proliferation
GO:0016310	phosphorylation
GO:0034976	response to endoplasmic reticulum stress
GO:0035621	ER to Golgi ceramide transport
GO:0055088	lipid homeostasis
GO:0070584	mitochondrion morphogenesis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001849 Pleckstrin homology domain
IPR002913 START domain

PFAM

PF00169
PF01852

PRINTS

PIRSF

SMART

SM00233
SM00234

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9GKI7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

286797

UniGene

Bt.7214

RefSeq

NP_777190

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF232931 AF232933

GenPept

AAG42047 AAG42049