Version 5.4
Bos taurus Protein: CDKN1C
Summary
InnateDB Protein IDBP-697874.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDKN1C
Protein Name cyclin-dependent kinase inhibitor 1C
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000041672
InnateDB Gene IDBG-645186 (CDKN1C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 protein binding
GO:0016301 kinase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001501 skeletal system development
GO:0001822 kidney development
GO:0001890 placenta development
GO:0007050 cell cycle arrest
GO:0007568 aging
GO:0016310 phosphorylation
GO:0030099 myeloid cell differentiation
GO:0030325 adrenal gland development
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033673 negative regulation of kinase activity
GO:0035264 multicellular organism growth
GO:0042326 negative regulation of phosphorylation
GO:0042551 neuron maturation
GO:0043010 camera-type eye development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050680 negative regulation of epithelial cell proliferation
GO:0055123 digestive system development
GO:0060065 uterus development
GO:0060669 embryonic placenta morphogenesis
GO:0071514 genetic imprinting
GO:0071901 negative regulation of protein serine/threonine kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003072 Orphan nuclear receptor, NOR1 type
IPR003175 Cyclin-dependent kinase inhibitor
PFAM PF02234
PRINTS PR01286
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2HJM8
UniProt Splice Variant
Entrez Gene 510972
UniGene Bt.4804
RefSeq NP_001071371
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY957984 DAAA02063708
GenPept ABD34312

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca