InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CLPX

Summary

InnateDB Protein

IDBP-698048.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLPX

Protein Name

ClpX caseinolytic peptidase X homolog (E. coli)

Synonyms

CILP;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011038

InnateDB Gene

IDBG-645334 (CLPX)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004176	ATP-dependent peptidase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008134	transcription factor binding
GO:0016504	peptidase activator activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0051082	unfolded protein binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006355	regulation of transcription, DNA-templated
GO:0006457	protein folding
GO:0010952	positive regulation of peptidase activity
GO:0051603	proteolysis involved in cellular protein catabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0009368	endopeptidase Clp complex
GO:0009841	mitochondrial endopeptidase Clp complex
GO:0042645	mitochondrial nucleoid

Protein Structure and Domains

PDB ID

InterPro

IPR002078 RNA polymerase sigma factor 54 interaction domain
IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR004487 Clp protease, ATP-binding subunit ClpX
IPR011704 ATPase, dynein-related, AAA domain
IPR019489 Clp ATPase, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00158
PF00004
PF07724
PF13304
PF07728
PF10431

PRINTS

PIRSF

SMART

SM00382
SM01086

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite