Version 5.4
Bos taurus Protein: ECE1
Summary
InnateDB Protein IDBP-698346.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ECE1
Protein Name Endothelin-converting enzyme 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000055669
InnateDB Gene IDBG-645619 (ECE1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0001921 positive regulation of receptor recycling
GO:0006508 proteolysis
GO:0007507 heart development
GO:0010814 substance P catabolic process
GO:0010815 bradykinin catabolic process
GO:0010816 calcitonin catabolic process
GO:0016485 protein processing
GO:0016486 peptide hormone processing
GO:0034959 endothelin maturation
GO:0042447 hormone catabolic process
GO:0042733 embryonic digit morphogenesis
GO:0043583 ear development
GO:0060037 pharyngeal system development
Cellular Component
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0033093 Weibel-Palade body
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008753 Peptidase M13, N-terminal domain
IPR018497 Peptidase M13, C-terminal domain
PFAM PF05649
PF01431
PRINTS PR00786
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q28868
UniProt Splice Variant
Entrez Gene 281133
UniGene Bt.4378
RefSeq NP_851352
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02006480 S73774
GenPept AAB32062

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca