Version 5.4
Bos taurus Protein: PITX1
Summary
InnateDB Protein IDBP-698595.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PITX1
Protein Name Paired-like homeodomain transcription factor 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006039
InnateDB Gene IDBG-645841 (PITX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001190 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001501 skeletal system development
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0014707 branchiomeric skeletal muscle development
GO:0021983 pituitary gland development
GO:0035116 embryonic hindlimb morphogenesis
GO:0035137 hindlimb morphogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048625 myoblast fate commitment
GO:0051216 cartilage development
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR003654 OAR domain
IPR009057 Homeodomain-like
IPR016233 Homeobox protein Pitx/unc30
PFAM PF00046
PF03826
PRINTS
PIRSF PIRSF000563
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1MW16
UniProt Splice Variant
Entrez Gene 508754
UniGene Bt.11284
RefSeq NP_001192229
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB257756 DAAA02020351
GenPept BAE93507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca