Version 5.4
Homo sapiens Protein: ST6GALNAC2
Summary
InnateDB Protein IDBP-69867.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST6GALNAC2
Protein Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Synonyms SAITL1; SIAT7; SIAT7B; SIATL1; ST6GalNAII; STHM;
Species Homo sapiens
Ensembl Protein ENSP00000225276
InnateDB Gene IDBG-69865 (ST6GALNAC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008373 sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0016266 O-glycan processing
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0097503 sialylation
Cellular Component
GO:0000139 Golgi membrane
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID
InterPro IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
PFAM PF00777
PRINTS
PIRSF PIRSF005557
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJ37
PhosphoSite PhosphoSite-Q9UJ37
TrEMBL A0A024R8M1
UniProt Splice Variant
Entrez Gene 10610
UniGene Hs.618925
RefSeq NP_006447
HUGO HGNC:10867
OMIM 610137
CCDS CCDS11747
HPRD 10231
IMGT
EMBL AJ251053 BC040455 BT019972 CH471099 U14550
GenPept AAA52228 AAH40455 AAV38775 CAB61434 EAW89417 EAW89418

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca