InnateDB Protein
|
IDBP-698839.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
WDR6
|
Protein Name
|
WD repeat-containing protein 6
|
Synonyms
|
|
Species
|
Bos taurus
|
Ensembl Protein
|
ENSBTAP00000025167
|
InnateDB Gene
|
IDBG-646066 (WDR6)
|
Protein Structure
|
|
Function |
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy. {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm {ECO:0000250}. Note=Colocalizes in the cytoplasm with STK11/LKB1. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
13 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001680
WD40 repeat
IPR011044
Quinoprotein amine dehydrogenase, beta chain-like
IPR017986
WD40-repeat-containing domain
|
PFAM |
PF00400
|
PRINTS |
|
PIRSF |
|
SMART |
SM00320
|
TIGRFAMs |
|
Modification |
|
SwissProt |
A7Z052
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
526884
|
UniGene |
Bt.7715
|
RefSeq |
NP_001099093
|
HUGO |
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
BC153250
|
GenPept |
AAI53251
|
|
|