InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ATP5S

Summary

InnateDB Protein

IDBP-699248.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP5S

Protein Name

ATP synthase subunit s, mitochondrial

Synonyms

FB;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020228

InnateDB Gene

IDBG-646443 (ATP5S)

Protein Structure

UniProt Annotation

Function

Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway. {ECO:0000269PubMed:12361715, ECO:0000269PubMed:18768789}.

Subcellular Localization

Mitochondrion. Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0046872	metal ion binding

Biological Process

GO:0006754	ATP biosynthetic process
GO:0006810	transport
GO:0006811	ion transport
GO:0015992	proton transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P22027

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

493709

UniGene

Bt.13666

RefSeq

NP_001007813

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AY780292 BC109757

GenPept

AAI09758 AAV52866