Version 5.4
Bos taurus Protein: GATA2
Summary
InnateDB Protein IDBP-699313.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GATA2
Protein Name GATA binding protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000026265
InnateDB Gene IDBG-646502 (GATA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001158 enhancer sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0070742 C2H2 zinc finger domain binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001655 urogenital system development
GO:0001709 cell fate determination
GO:0001892 embryonic placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0021514 ventral spinal cord interneuron differentiation
GO:0021533 cell differentiation in hindbrain
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain
GO:0021954 central nervous system neuron development
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0035019 somatic stem cell maintenance
GO:0035065 regulation of histone acetylation
GO:0035854 eosinophil fate commitment
GO:0042472 inner ear morphogenesis
GO:0045599 negative regulation of fat cell differentiation
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045650 negative regulation of macrophage differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048469 cell maturation
GO:0048663 neuron fate commitment
GO:0048873 homeostasis of number of cells within a tissue
GO:0060216 definitive hemopoiesis
GO:0060872 semicircular canal development
GO:0070345 negative regulation of fat cell proliferation
GO:0097154 GABAergic neuron differentiation
GO:2000178 negative regulation of neural precursor cell proliferation
GO:2000977 regulation of forebrain neuron differentiation
Cellular Component
GO:0005634 nucleus
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR000679 Zinc finger, GATA-type
IPR016374 Transcription factor, GATA-1/2/3
PFAM PF00320
PRINTS PR00619
PIRSF PIRSF003027
SMART SM00401
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BAM5
UniProt Splice Variant
Entrez Gene 506809
UniGene Bt.91285
RefSeq NP_001179043
HUGO HGNC:4171
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054682
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca