InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RUVBL1

Summary

InnateDB Protein

IDBP-699319.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUVBL1

Protein Name

ruvB-like 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027964

InnateDB Gene

IDBG-646505 (RUVBL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 172 interaction(s) predicted by orthology.

Predicted by orthology
Total	172 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003678	DNA helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0009378	four-way junction helicase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0043967	histone H4 acetylation
GO:0043968	histone H2A acetylation

Cellular Component

GO:0000812	Swr1 complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0031011	Ino80 complex
GO:0035267	NuA4 histone acetyltransferase complex
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome
GO:0071339	MLL1 complex

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR010339 TIP49, C-terminal
IPR012340 Nucleic acid-binding, OB-fold
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF05496
PF06068

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite