InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.102247

Summary

InnateDB Protein

IDBP-699346.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.102247

Protein Name

ras GTPase-activating protein 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000012583

InnateDB Gene

IDBG-646529 (BT.102247)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.

Predicted by orthology
Total	53 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005096	GTPase activator activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0051020	GTPase binding

Biological Process

GO:0001953	negative regulation of cell-matrix adhesion
GO:0007162	negative regulation of cell adhesion
GO:0007165	signal transduction
GO:0030833	regulation of actin filament polymerization
GO:0043547	positive regulation of GTPase activity
GO:0051056	regulation of small GTPase mediated signal transduction

Cellular Component

GO:0001726	ruffle
GO:0005622	intracellular
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000980 SH2 domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR001936 Ras GTPase-activating protein
IPR008936 Rho GTPase activation protein

PFAM