Version 5.4
Bos taurus Protein: FBN1
Summary
InnateDB Protein IDBP-699507.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBN1
Protein Name fibrillin-1 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002944
InnateDB Gene IDBG-646680 (FBN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001501 skeletal system development
GO:0007507 heart development
Cellular Component
GO:0001527 microfibril
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011398 Fibrillin/Microneme protein4
IPR017878 TB domain
PFAM PF00008
PF07645
PF00683
PRINTS
PIRSF PIRSF036312
SMART SM00181
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8HY63
UniProt Splice Variant
Entrez Gene 281154
UniGene Bt.107024
RefSeq NP_776478
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY162463 DAAA02029120 DAAA02029121 DAAA02029122
GenPept AAN85441

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca