Version 5.4
Bos taurus Protein: PSEN1
Summary
InnateDB Protein IDBP-699668.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSEN1
Protein Name Presenilin-1Presenilin-1 NTF subunitPresenilin-1 CTF subunitPresenilin-1 CTF12
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000015615
InnateDB Gene IDBG-646832 (PSEN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 120 interaction(s) predicted by orthology.
Predicted by orthology
Total 120 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0035556 intracellular signal transduction
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001108 Peptidase A22A, presenilin
IPR002031 Peptidase A22A, presenilin 1
IPR006639 Presenilin/signal peptide peptidase
PFAM PF01080
PRINTS PR01072
PR01073
PIRSF
SMART SM00730
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A7MBA9
UniProt Splice Variant
Entrez Gene 282705
UniGene Bt.51581
RefSeq XP_005211993
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151458 DAAA02029591 DAAA02029592 DAAA02029593
GenPept AAI51459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca