Version 5.4
Bos taurus Protein: BT.64612
Summary
InnateDB Protein IDBP-699671.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.64612
Protein Name protein numb homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052600
InnateDB Gene IDBG-646834 (BT.64612)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
Biological Process
GO:0007399 nervous system development
GO:0007405 neuroblast proliferation
GO:0007409 axonogenesis
GO:0021670 lateral ventricle development
GO:0021849 neuroblast division in subventricular zone
GO:0030862 positive regulation of polarized epithelial cell differentiation
GO:0030900 forebrain development
GO:0034332 adherens junction organization
GO:0045746 negative regulation of Notch signaling pathway
GO:0050769 positive regulation of neurogenesis
GO:0060487 lung epithelial cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0016323 basolateral plasma membrane
GO:0019897 extrinsic component of plasma membrane
GO:0045177 apical part of cell
Protein Structure and Domains
PDB ID
InterPro IPR006020 PTB/PI domain
IPR010449 NUMB domain
IPR016698 Numb/numb-like
PFAM PF00640
PF14719
PF06311
PRINTS
PIRSF PIRSF017607
SMART SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1B8G1
UniProt Splice Variant
Entrez Gene 512187
UniGene Bt.64612
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02029594 DAAA02029595
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca