Version 5.4
Bos taurus Protein: NGB
Summary
InnateDB Protein IDBP-699733.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NGB
Protein Name Neuroglobin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021661
InnateDB Gene IDBG-646891 (NGB)
Protein Structure
UniProt Annotation
Function Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity). {ECO:0000250}.
Subcellular Localization Perikaryon {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
GO:0015671 oxygen transport
Cellular Component
GO:0043204 perikaryon
Protein Structure and Domains
PDB ID
InterPro IPR000971 Globin
IPR009050 Globin-like
PFAM PF00042
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6WZ19
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 414920
UniGene
RefSeq NP_001001853
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ635234
GenPept CAG25616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca