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InnateDB Protein
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IDBP-700030.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RGS9BP
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Protein Name
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Regulator of G-protein signaling 9-binding protein
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000048052
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InnateDB Gene
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IDBG-647181 (RGS9BP)
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Protein Structure
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| Function |
Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Specifically expressed in the retina. Only present in photoreceptors (at protein level). {ECO:0000269PubMed:12119397}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
1 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q8MJG0
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
282338
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| UniGene |
Bt.13034
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| RefSeq |
NP_001159988
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AF480475
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| GenPept |
AAM67417
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Version 5.4