Version 5.4
Homo sapiens Protein: METTL23
Summary
InnateDB Protein IDBP-70050.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METTL23
Protein Name methyltransferase like 23
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000341543
InnateDB Gene IDBG-70048 (METTL23)
Protein Structure
UniProt Annotation
Function Probable methyltransferase. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:23349634}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=When overexpressed, detected in cytoplasmic membrane-like structures.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR019410 Nicotinamide N-methyltransferase-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF10294
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XA0
PhosphoSite PhosphoSite-Q86XA0
TrEMBL K7EPT5
UniProt Splice Variant
Entrez Gene 124512
UniGene Hs.596452
RefSeq XP_006721735
HUGO HGNC:26988
OMIM 615262
CCDS CCDS45787
HPRD
IMGT
EMBL AC005837 BC045819 CH471099 JQ313903
GenPept AAH45819 AFH41797 EAW89435 EAW89437 EAW89438

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca