Version 5.4
Homo sapiens Protein: OPA1
Summary
InnateDB Protein IDBP-70074.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OPA1
Protein Name optic atrophy 1 (autosomal dominant)
Synonyms largeG; MGM1; NPG; NTG;
Species Homo sapiens
Ensembl Protein ENSP00000355324
InnateDB Gene IDBG-70072 (OPA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001401 Dynamin, GTPase domain
IPR022812 Dynamin superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00350
PRINTS PR00195
PIRSF
SMART SM00053
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6PEK6
UniProt Splice Variant
Entrez Gene 4976
UniGene Hs.743613
RefSeq NP_570850
HUGO HGNC:8140
OMIM 605290
CCDS
HPRD 05596
IMGT
EMBL AC048351 AC106710 BC058013 CH471052 HQ204906 HQ204907 HQ204908 HQ204910 HQ204911 HQ204912 HQ204913 HQ204914 HQ204917 HQ204918 HQ204920 HQ204921 HQ204922 HQ204923 HQ204924 HQ204925 HQ204926 HQ204927 HQ204929 HQ204930 HQ204932 HQ204933 HQ204934 HQ204935 HQ204936 HQ204938 HQ204939 HQ204940 HQ204941 HQ204942 HQ204943 HQ204944 HQ204945
GenPept AAH58013 ADP90054 ADP90062 ADP90070 ADP90086 ADP90094 ADP90102 ADP90110 ADP90118 ADP90142 ADP90150 ADP90166 ADP90174 ADP90182 ADP90190 ADP90198 ADP90206 ADP90214 ADP90222 ADP90238 ADP90246 ADP90262 ADP90270 ADP90278 ADP90286 ADP90294 ADP90310 ADP90318 ADP90326 ADP90334 ADP90342 ADP90350 ADP90358 ADP90366 EAW78070

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca