Version 5.4
Bos taurus Protein: THBD
Summary
InnateDB Protein IDBP-701477.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THBD
Protein Name thrombomodulin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052487
InnateDB Gene IDBG-648758 (THBD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007165 signal transduction
GO:0007565 female pregnancy
GO:0007596 blood coagulation
Cellular Component
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001304 C-type lectin
IPR001491 Thrombomodulin
IPR001881 EGF-like calcium-binding domain
IPR015149 Thrombomodulin-like, EGF-like
IPR016187 C-type lectin fold
IPR016316 Complement component C1q/Thrombomodulin
PFAM PF00008
PF00059
PF07645
PF09064
PRINTS PR00907
PIRSF PIRSF001775
SMART SM00181
SM00034
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N6M2
UniProt Splice Variant
Entrez Gene 281529
UniGene Bt.471
RefSeq NP_001159994
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035852
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca