Version 5.4
| Bos taurus Protein: PFN3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-701485.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PFN3 | ||||||||
| Protein Name | Profilin-3 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000054439 | ||||||||
| InnateDB Gene | IDBG-648767 (PFN3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Binds to actin and affects the structure of the cytoskeleton. Binds to poly-L-proline, phosphatidylinositol 3- phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). Slightly reduces actin polymerization. May be involved in spermatogenesis. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR005454
Profilin, chordates IPR005455 Profilin |
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| PFAM |
PF00235
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| PRINTS |
PR01639
PR00392 PR01640 |
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| PIRSF | |||||||||
| SMART |
SM00392
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q32PB1 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 521379 | ||||||||
| UniGene | Bt.54239 | ||||||||
| RefSeq | NP_001071413 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC108188 | ||||||||
| GenPept | AAI08189 | ||||||||