InnateDB Protein
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IDBP-7019.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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H1F0
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Protein Name
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H1 histone family, member 0
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Synonyms
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H10; H1FV;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000344504
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InnateDB Gene
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IDBG-7017 (H1F0)
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Protein Structure
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Function |
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00837, ECO:0000269PubMed:18993075}. Chromosome {ECO:0000255PROSITE-ProRule:PRU00837, ECO:0000269PubMed:18993075}. Note=The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
32
[view]
|
Protein-Protein |
32
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR005818
Linker histone H1/H5, domain H15
IPR005819
Histone H5
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PFAM |
PF00538
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PRINTS |
PR00624
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PIRSF |
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SMART |
SM00526
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TIGRFAMs |
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Modification |
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SwissProt |
P07305
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PhosphoSite |
PhosphoSite-P07305
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
3005
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UniGene |
Hs.226117
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RefSeq |
NP_005309
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HUGO |
HGNC:4714
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OMIM |
142708
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CCDS |
CCDS13956
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HPRD |
00819
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IMGT |
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EMBL |
AK299209
AK312583
BC000145
BC029046
CH471095
CR456502
CR542220
X03473
Z97630
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GenPept |
AAH00145
AAH29046
BAG35477
BAG61248
CAA27190
CAB42829
CAG30388
CAG47016
EAW60188
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