Version 5.4
Homo sapiens Protein: TMEM2
Summary
InnateDB Protein IDBP-70287.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM2
Protein Name transmembrane protein 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366266
InnateDB Gene IDBG-70285 (TMEM2)
Protein Structure
UniProt Annotation
Function May be required for the heart morphogenesis. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:10767548}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR011050 Pectin lyase fold/virulence factor
IPR019316 G8 domain
PFAM PF10162
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHN6
PhosphoSite PhosphoSite-Q9UHN6
TrEMBL B4E1B9
UniProt Splice Variant
Entrez Gene 23670
UniGene Hs.630735
RefSeq NP_001129292
HUGO HGNC:11869
OMIM 605835
CCDS CCDS47979
HPRD 09317
IMGT
EMBL AB037833 AF137030 AK027818 AK075370 AK303765 AL161732 AL671309 BC140773 BC146780 CH471089
GenPept AAF21348 AAI40774 AAI46781 BAA92650 BAC11574 BAG51381 BAG64731 CAI15172 CAI15173 CAI15174 CAI15175 CAI15176 EAW62518

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca