InnateDB Protein
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IDBP-70437.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMEM86B
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Protein Name
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transmembrane protein 86B
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000321038
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InnateDB Gene
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IDBG-70435 (TMEM86B)
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Protein Structure
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Function |
Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties. {ECO:0000269PubMed:21515882}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:21515882}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0047408
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alkenylglycerophosphocholine hydrolase activity
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GO:0047409
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alkenylglycerophosphoethanolamine hydrolase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR012506
YhhN-like
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PFAM |
PF07947
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N661
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
255043
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UniGene |
Hs.135215
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RefSeq |
NP_776165
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HUGO |
HGNC:28448
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OMIM |
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CCDS |
CCDS12920
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HPRD |
14540
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IMGT |
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EMBL |
AC010327
BC023000
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GenPept |
AAH23000
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