InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BMS1

Summary

InnateDB Protein

IDBP-70989.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BMS1

Protein Name

BMS1 homolog, ribosome assembly protein (yeast)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000363642

InnateDB Gene

IDBG-70987 (BMS1)

Protein Structure

UniProt Annotation

Function

May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0042254	ribosome biogenesis
GO:0042255	ribosome assembly

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR007034 Ribosome biogenesis protein BMS1/TSR1, C-terminal
IPR012948 AARP2CN
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF04950
PF08142

PRINTS

PR00315

PIRSF

SMART

SM00785

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q14692

PhosphoSite

PhosphoSite-Q14692

TrEMBL

UniProt Splice Variant

Entrez Gene

9790

UniGene

Hs.10848

RefSeq

NP_055568

HUGO

HGNC:23505

OMIM

611448

CCDS

CCDS7199

HPRD

10689

IMGT

EMBL

AL022344 BC043345 BC150252 CH471160 D80009

GenPept

AAH43345 AAI50253 BAA11504 CAI23617 EAW86571