InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: C1QTNF1

Summary

InnateDB Protein

IDBP-71080.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

C1QTNF1

Protein Name

C1q and tumor necrosis factor related protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000343230

InnateDB Gene

IDBG-71074 (C1QTNF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding

Biological Process

GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0010544	negative regulation of platelet activation
GO:0010628	positive regulation of gene expression
GO:0090331	negative regulation of platelet aggregation
GO:2000860	positive regulation of aldosterone secretion

Cellular Component

GO:0005576	extracellular region
GO:0005581	collagen trimer
GO:0005615	extracellular space
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001073 Complement C1q protein
IPR008160 Collagen triple helix repeat
IPR008983 Tumour necrosis factor-like domain

PFAM

PF00386
PF01391

PRINTS

PR00007

PIRSF

SMART

SM00110

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC073624 AF232905 AF329840 AJ272138 AK055541 AK075175 AK172767 AY358424 BC021553

GenPept

AAG44303 AAH21553 AAK17964 AAQ88790 BAB70947 BAC11451 BAD18750 CAC20425

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca