Mus musculus Protein: Foxg1
Summary
InnateDB Protein IDBP-713420.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxg1
Protein Name
Synonyms 2900064B05Rik; BF-1; Bf1; Hfh9; Hfhbf1;
Species Mus musculus
Ensembl Protein ENSMUSP00000136372
InnateDB Gene IDBG-137578 (Foxg1)
Protein Structure
UniProt Annotation
Function Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. {ECO:0000250}.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity CNS, and nasal half of the retina.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0002052 positive regulation of neuroblast proliferation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007346 regulation of mitotic cell cycle
GO:0007568 aging
GO:0009953 dorsal/ventral pattern formation
GO:0010468 regulation of gene expression
GO:0016199 axon midline choice point recognition
GO:0021852 pyramidal neuron migration
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0030900 forebrain development
GO:0042472 inner ear morphogenesis
GO:0045665 negative regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048664 neuron fate determination
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0051726 regulation of cell cycle
GO:2000177 regulation of neural precursor cell proliferation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1347464
InterPro IPR001766 Transcription factor, fork head
PFAM PF00250
PRINTS PR00053
PIRSF
SMART SM00339
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60987
PhosphoSite PhosphoSite-Q60987
TrEMBL Q3V1Q8
UniProt Splice Variant
Entrez Gene 15228
UniGene Mm.478178
RefSeq NP_001153584
MGI ID
MGI Symbol Foxg1
OMIM
CCDS CCDS25899
HPRD
IMGT
EMBL AK132305 BC046958 U36760
GenPept AAB42158 AAH46958 BAE21092