InnateDB Protein
|
IDBP-717511.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Kcnmb2
|
Protein Name
|
|
Synonyms
|
2700049B16Rik; 3110031N04Rik;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000136596
|
InnateDB Gene
|
IDBG-136457 (Kcnmb2)
|
Protein Structure
|
|
Function |
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0015269
|
calcium-activated potassium channel activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1919663
|
InterPro |
IPR003930
Potassium channel, calcium-activated, BK, beta subunit
IPR015382
KCNMB2, ball/chain domain
|
PFAM |
PF03185
PF09303
|
PRINTS |
PR01450
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9CZM9
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
72413
|
UniGene |
Mm.64790
|
RefSeq |
XP_006535611
|
MGI ID |
|
MGI Symbol |
Kcnmb2
|
OMIM |
|
CCDS |
CCDS17292
|
HPRD |
|
IMGT |
|
EMBL |
AK012400
AY062429
BC046227
BC058957
|
GenPept |
AAH46227
AAH58957
AAL38982
BAB28216
|
|
|