InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTPRC

Summary

InnateDB Protein

IDBP-722219.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPRC

Protein Name

Synonyms

B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200;

Species

Homo sapiens

Ensembl Protein

ENSP00000469141

InnateDB Gene

IDBG-105609 (PTPRC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	72 [view]
Protein-Protein	72 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0045087	innate immune response (InnateDB)
GO:0050852	T cell receptor signaling pathway

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR003961 Fibronectin, type III
IPR016335 Leukocyte common antigen
IPR024739 Protein tyrosine phosphatase, receptor type, N-terminal
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00041
PF01108
PF12567
PF12453

PRINTS

PR00700

PIRSF

PIRSF002004

SMART

SM00194
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References