Homo sapiens Protein: ARHGEF9
Summary
InnateDB Protein IDBP-73043.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF9
Protein Name Cdc42 guanine nucleotide exchange factor (GEF) 9
Synonyms COLLYBISTIN; EIEE8; HPEM-2; PEM-2; PEM2;
Species Homo sapiens
Ensembl Protein ENSP00000364012
InnateDB Gene IDBG-73041 (ARHGEF9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR011511 Variant SH3 domain
PFAM PF00621
PF00018
PF14604
PF00169
PF07653
PRINTS PR00452
PIRSF
SMART SM00325
SM00326
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AMR4
UniProt Splice Variant
Entrez Gene 23229
UniGene Hs.54697
RefSeq
HUGO HGNC:14561
OMIM 300429
CCDS
HPRD 02337
IMGT
EMBL AL355142 AL391277 AL451106
GenPept