InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DRGX

Summary

InnateDB Protein

IDBP-73916.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DRGX

Protein Name

dorsal root ganglia homeobox

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000363254

InnateDB Gene

IDBG-73914 (DRGX)

Protein Structure

UniProt Annotation

Function

Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108, ECO:0000255PROSITE-ProRule:PRU00138}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001764	neuron migration
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0007399	nervous system development
GO:0007409	axonogenesis
GO:0007411	axon guidance
GO:0009593	detection of chemical stimulus
GO:0016048	detection of temperature stimulus
GO:0021516	dorsal spinal cord development
GO:0021559	trigeminal nerve development
GO:0030182	neuron differentiation
GO:0050954	sensory perception of mechanical stimulus