InnateDB Protein
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IDBP-73981.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IFT46
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Protein Name
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intraflagellar transport 46 homolog (Chlamydomonas)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000264021
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InnateDB Gene
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IDBG-73977 (IFT46)
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Protein Structure
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Function |
Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Note=Expression is concentrated at the cilium basal body but is also detected along the length of the cilium. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR022088
Intraflagellar transport complex B protein 46
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PFAM |
PF12317
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NQC8
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PhosphoSite |
PhosphoSite-Q9NQC8
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TrEMBL |
E9PSB9
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UniProt Splice Variant |
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Entrez Gene |
56912
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UniGene |
Hs.533738
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RefSeq |
NP_001162089
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HUGO |
HGNC:26146
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OMIM |
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CCDS |
CCDS53718
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HPRD |
07967
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IMGT |
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EMBL |
AJ249980
AK025480
AK289521
AL136934
AP000941
BC011647
BC012802
BC022856
CR457344
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GenPept |
AAH11647
AAH12802
AAH22856
BAB15146
BAF82210
CAB66868
CAB96537
CAG33625
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