Version 5.4
Homo sapiens Protein: MGA
Summary
InnateDB Protein IDBP-745036.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MGA
Protein Name
Synonyms MAD5; MXD5;
Species Homo sapiens
Ensembl Protein ENSP00000456141
InnateDB Gene IDBG-7233 (MGA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0071339 MLL1 complex
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00907
PF00010
PRINTS PR00937
PIRSF
SMART SM00425
SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IWI9
PhosphoSite PhosphoSite-Q8IWI9
TrEMBL H3BTF4
UniProt Splice Variant
Entrez Gene 23269
UniGene Hs.713921
RefSeq
HUGO HGNC:14010
OMIM
CCDS CCDS55960
HPRD
IMGT
EMBL AB011090 AC016134 AC073657 AK022696 AK023360 AL050181 BC038449
GenPept AAH38449 BAA25444 BAB14186 BAB14543 CAB43310

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca